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The Big 3

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The Big 3

Postby spex » Wed Apr 30, 2008 11:25 am

The “Big 3”

The big 3 to beat DHT, THE CAUSE OF HAIRLOSS!

- Propecia ( Finasteride ), Minoxidil and Nizoral

Here is the thing you need to make sure you understand when it comes to MPB:

The main known factor that causes hairloss is DHT. To form DHT your body's 5a-reductase enzyme converts free roaming testosterone DHT inside the hair cell follicle. The DHT then binds to the hair cell receptor and causes it to atrophy or shrink. Eventually your hair follicle stops producing hair and you lose that follicle.

There are two types of the 5ar enzyme; Type I and Type II. Type II 5ar seems to be the main culprit in MPB as the type II enzyme is present in the hair follicles. Finasteride is a specific inhibitor of Type II 5ar inhibitor that reduces DHT produced by the type II 5ar by 85%-90% and reduces the overall DHT blood serum levels by 65%.

As you can see Finasteride (PROPECIA ) is extremely useful as a treatment for MPB as it directly attacks the problem. Nizoral shampoo is thought to help "dull" the androgen receptors in the scalp which the DHT binds to. Together they provide a synergetic effect.

Minoxidil is a hair stimulant. It is the only FDA proven hair stimulant on the market. However stimulating hair and protecting hair from further damage are two separate actions

Minoxidil will artificially augment your hair while you use the compound but it does NOT have any know effect on 5ar or the androgen receptors in the scalp.

The best way to attack MPB is to:

1. Stop further damage to your hair via DHT. You can accomplish this best by using Finasteride to inhibit the 5ar enzyme and Nizoral to "dull" the androgen receptors.

2. **If** further thickening/regrowth is needed after the hair damaging DHT androgen is reduced then minoxidil can be used to further augment your existing hairs and perhaps even stimulant some dormant hair follicles to resume growing.

Use all these 3 products together -

1. Minoxidil 2 x a day - once in the am and once in the pm
2. Finesteride (propecia/proscar) 1mg per day
3. Nizoral 2 x a weeks (no more) - will dry your scalp out!
Posts: 8
Joined: Wed Apr 30, 2008 11:19 am

Re: The Big 3

Postby CountryBoy » Tue Aug 11, 2009 5:56 pm

Thanks spex,

I'm interested though, I take propecia and am starting to use Nizoral, I thought it was Minoxidil that dried your scalp not using Nizoral too often?

Posts: 19
Joined: Wed Jun 10, 2009 12:42 pm

Re: The Big 3

Postby mania » Fri Dec 18, 2020 7:51 am

Hmm ! That's right for someting that you used such prodcuts can aslo cause you hair loss then it's better not used it regularly but it's better to follow the advice of dermotalogist for permanent hair loss go for fue hair restoration in Islamabad for better treatment.
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Joined: Sun Nov 06, 2016 10:20 am
Location: Pakistan

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